Topic Library

Browse Clinical Topics

Explore high-yield PLAB 1 topics. Each one is taught through three perspectives with practice MCQs.

Dermatology

1 topic

Acne Vulgaris

Dermatology

Acne vulgaris — the most common skin condition in adolescents and young adults. Covers pathophysiology, classification (comedonal, inflammatory, nodulocystic), stepwise management per NICE CKS, isotretinoin prescribing, and the Pregnancy Prevention Programme.

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Dermatology / Surgery

1 topic

easy

A Clinical Guide to Common Benign Skin Cysts and Nodules

Dermatology / Surgery

A comprehensive guide to common benign skin cysts and nodules — epidermoid cysts, pilar cysts, lipomas, dermoid cysts, and ganglion cysts. Covers clinical features, distinguishing characteristics, and management per NICE CKS guidelines.

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Gastroenterology

1 topic

medium

Achalasia

Gastroenterology

Achalasia — failure of the lower oesophageal sphincter to relax due to degeneration of the myenteric plexus. Covers presentation, barium swallow findings, manometry, and stepwise management per NICE and BSG guidelines.

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Neurology

1 topic

medium

Absence Seizure

Neurology

Generalised absence seizures — brief episodes of impaired awareness with abrupt onset and offset, most common in childhood. A high-yield PLAB 1 topic covering diagnosis, EEG findings, and first-line management per NICE CG137.

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Neurology / Psychiatry

1 topic

medium

Acute Dystonia

Neurology / Psychiatry

Acute dystonic reactions — sudden involuntary muscle contractions caused by dopamine-blocking drugs. A high-yield PLAB 1 topic covering diagnosis, management, and pharmacology.

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Orthopaedics / Musculoskeletal

1 topic

easy

Achilles Tendon Rupture

Orthopaedics / Musculoskeletal

Achilles tendon rupture — acute rupture of the largest tendon in the body. Covers clinical diagnosis (Simmonds/Thompson test), risk factors including fluoroquinolones and corticosteroids, and management options per NICE CKS guidelines.

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Pharmacology / Nephrology

1 topic

hard

ACE Inhibitors and Renal Impairment

Pharmacology / Nephrology

ACE inhibitors in the context of renal impairment — understanding when they protect the kidneys and when they cause harm. Covers NICE guidelines on monitoring, contraindications, and the critical creatinine/potassium thresholds for PLAB 1.

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